The link between the vaginal microbiome and fertility is one of the most exciting areas in emerging research. And while there’s still more to learn, there’s growing evidence that the state of your vaginal microbiome can impact your reproductive journey.
We know that navigating infertility can feel overwhelming, with many factors to consider and options to explore. While the science connecting the vaginal microbiome and fertility is still evolving, testing your vaginal microbiome with Evvy can offer valuable insights into what’s happening in your body.
For example, high levels of disruptive bacteria like Gardnerella may signal a state of dysbiosis — an imbalance that research has linked to lower chances of conception. If your Evvy results suggest this, it could be a valuable starting point for a conversation with your provider about steps to help restore a more protective microbiome.
In general, studies suggest that having a vaginal microbiome dominated by protective Lactobacillus species is associated with better fertility outcomes. On the other hand, imbalances in the vaginal microbiome — known as vaginal dysbiosis — have been linked to challenges with conception. That said, remember this isn't a hard and fast rule, but just an association.
It’s also important to remember that research varies depending on what part of the reproductive tract is studied (vaginal, cervical, or endometrial microbiomes) and whether conception is being attempted naturally or through IUI or IVF.
But we do know this: bacterial vaginosis (BV), one of the most common vaginal infections, has been linked to higher risks of STIs — which, if left untreated, can lead to pelvic inflammatory disease (PID) and potential fertility issues down the line. That’s why routine STI testing is especially important when planning for pregnancy.
Groundbreaking research links the vaginal microbiome to fertility outcomes, including implantation rates and IVF success outcomes. Evvy now measures 4 Microbiome Markers associated with fertility (and highlights where your results fall within the optimal ranges based on the latest research):
Protective Score: the percentage of protective bacteria in your microbiome
Why? A Lactobacillus-dominant microbiome fosters a stable, low-pH environment that supports conception. Research suggests this protective balance may enhance the ability to achieve pregnancy - whether naturally or through IVF.
Microbiome Diversity Score: how many different kinds of bacteria are present
Why? High microbiome diversity - or the presence of too many disruptive species - can disrupt your vaginal microbiome balance. Studies associate lower microbiome diversity with improved fertility and IVF outcomes.
Fertility Disruptors: checks for five bacteria associated with negative fertility outcomes
Why? Certain disruptive bacteria, such as Fannyhessae, Gardnerella, Prevotella, Sneathia, and Ureaplasma have been associated with negative fertility outcomes.
STI Status: included with our Expanded PCR Panel, testing for 4 common STIs*
Why? Sexually transmitted infections are directly linked to infertility and pregnancy complications.
Your fertility journey is uniquely yours. Our mission is to give you the insights, tools, and support to better understand your body — and advocate for the care you deserve.
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